Background & Aim: The purpose of this study was to evaluate the MICRO-shear bond strength of two kinds of resin-based cements with fluoride release with the usage of five adhesive systems to enamel and dentin. Materials & methods: Bovine flat enamel or dentin surfaces were used in this study. MICRO cylinders of resin cement with Xeno Cem Plus (XCP) or Panavia Fluoro Cement (PFC) were bonded to enamel or dentin as followed: XCP or PFC as instructions prior to the usage of their own adhesive systems, Xeno CF II+XCP, SE Bond+PFC, or Clearfil Liner Bond II (CLB) + PFC. After the storage in 37°c water for 24 hrs, MICRO-shear bond test was applied for all the test groups. The data were statistically analyzed using two-way analysis of variance (ANOVA). After two-way ANOVA, one-way ANOVA and multiple comparisons with Fishers PLSD test were made.Results: Are given as follow (enamel and dentin, mean±SD in MPa); XCP, 13.7±4.0 and 15.5±9.2; PFC, 23.7±10.6 and 15.0±7.3; XCP+XCF II, 35.4±11.5 and 17.1±4.0; PFC+SE, 54.2±9.8 and 41.7±12.0; PFCCLB, 31.39±3.09 and 15.09±4.35. ANOVA (α=0.05) analyze revealed the usage of SE Bond under PFC significantly increased the bond strength to both enamel and dentin. Bonding of Xeno CFII was only improved the bonding to enamel with the application of XCP.Conclusion: Light-cure adhesive systems significantly improve the bonding of current resin cements.